The Great River Road is one of America’s most iconic scenic routes, stretching nearly 3,000 miles along the Mississippi River. This National Scenic Byway travels through ten states and offers a mix of small river towns, historic sites, wildlife refuges, and breathtaking viewpoints. Whether you are planning a full-length Mississippi River road trip or exploring one state at a time, this guide gives you everything you need for a smooth, memorable journey.
This Great River Road trip guide covers the best stops, attractions, state-by-state highlights, and essential travel tips.
Why Take the Great River Road Trip?
This road trip captures the heart of America. You’ll drive through farmland, forests, historic cities, and vibrant cultural destinations, all while following the path of the Mississippi River.
Highlights of the Route
- Scenic overlooks and river viewpoints
- National wildlife refuges and parks
- Historic Civil War sites
- Charming small towns
- Local food, music, and roadside attractions
Great River Road Overview
| State | Major Stops | Key Highlights |
|---|---|---|
| Minnesota | Itasca State Park, Minneapolis | Mississippi River Headwaters |
| Wisconsin | La Crosse, Pepin | Bluffs, river towns |
| Iowa | Dubuque, Davenport | Scenic byways, museums |
| Illinois | Galena, Quad Cities | Historic districts |
| Missouri | St. Louis, Ste. Genevieve | Gateway Arch, French heritage |
| Kentucky | Wickliffe | River viewpoints |
| Tennessee | Memphis | Blues, barbecue |
| Arkansas | Helena, Lake Village | Delta heritage |
| Mississippi | Vicksburg, Natchez | Civil War history |
| Louisiana | Baton Rouge, New Orleans | Culture, music, cuisine |
Best Stops on the Great River Road Trip
Minnesota: Mississippi River Headwaters
Begin your journey at Itasca State Park, where the Mississippi River starts as a small stream.
Top Stops
- Itasca State Park
- Bemidji
- Minneapolis Riverfront
Wisconsin: River Bluffs and Small Towns
This region offers some of the best river views on the entire route.
Highlights
- La Crosse Grandad Bluff
- Pepin Marina
- Alma Overlook
Iowa: Scenic Byways and Museums
Iowa’s section is known for rolling hills and historic riverfront towns.
Must-See
- Dubuque Mississippi River Museum
- Pikes Peak State Park
- Davenport riverfront
Illinois: Historic Towns and Riverfront Views
Illinois features charming neighborhoods and classic Midwestern scenery.
Best Stops
- Galena Historic District
- Quad Cities
- Nauvoo State Historic Site
Missouri: Gateway Arch and French History
A central highlight of the Great River Road trip.
Key Attractions
- Gateway Arch National Park
- St. Charles Historic District
- Ste. Genevieve
Kentucky: Peaceful River Landscapes
Kentucky’s short stretch offers scenic stops and river viewpoints.
Don’t Miss
- Wickliffe Mounds State Historic Site
Tennessee: Memphis and the Delta
A major cultural highlight of the Mississippi River road trip.
Memphis Highlights
- Beale Street
- National Civil Rights Museum
- Graceland
Arkansas: Delta Culture and Heritage
Experience the roots of blues, farming culture, and quiet rural roads.
Stops Include
- Helena’s Blues Heritage Sites
- Lake Chicot State Park
Mississippi: History and River Towns
This section offers significant Civil War history and classic Southern charm.
Must-Visit
- Vicksburg National Military Park
- Natchez Trace Overlook
- Natchez Historic Homes
Louisiana: The Final Stretch to the Gulf
End your road trip with culture, food, and music.
Top Louisiana Stops
- Baton Rouge
- Plantation River Road
- New Orleans French Quarter
Best Time to Drive the Great River Road
The Great River Road is accessible year-round, but certain seasons offer better conditions.
Seasonal Guide
- Spring: Mild weather and green landscapes
- Summer: River festivals and long daylight
- Fall: Peak foliage in northern states
- Winter: Limited access in the north but fewer crowds
Essential Travel Tips for the Great River Road
What to Pack
- Layered clothing for changing climates
- Reusable water bottle
- Phone charger and offline maps
- Comfortable walking shoes
- Travel cooler for long stretches
Driving Tips
- Allow extra time for scenic pull-offs
- Expect slower travel through small towns
- Check ferry schedules where applicable
- Plan lodging ahead in peak seasons
Suggested Itinerary: 7-Day Great River Road Trip
| Day | Route | Major Stops |
|---|---|---|
| Day 1 | Minnesota to Wisconsin | Itasca State Park, Minneapolis |
| Day 2 | Wisconsin | La Crosse, Pepin |
| Day 3 | Iowa | Dubuque, Pikes Peak State Park |
| Day 4 | Illinois to Missouri | Galena, St. Louis |
| Day 5 | Tennessee | Memphis |
| Day 6 | Arkansas to Mississippi | Helena, Vicksburg |
| Day 7 | Louisiana | Baton Rouge, New Orleans |
Final Thoughts
A Great River Road trip along the Mississippi is one of the most rewarding long-distance drives in the United States. With scenic landscapes, historic towns, cultural attractions, and authentic regional food, this guide gives you everything you need to plan the perfect journey. Whether you follow the full 3,000 miles or explore one state at a time, the experience is unforgettable.
